Mo Hashemian
Mo is originally from Irvine, California, and earned his PhD at the University of California, Davis. There, he conducted research in Sheila David’s laboratory, focusing on DNA damage and repair. His work combined protein X-ray crystallography with enzymological assays to investigate the structural and functional roles of two metal cofactors in the enzyme MUTYH – a 4Fe-4S cluster and a mononuclear zinc ion – and their contributions to DNA repair mechanisms. Here, Mo aims to determine crystallographic structures of M-type cross-reactive antibodies bound to M proteins, advancing the understanding of immune recognition of Group A Streptococcus and thereby informing the rational design of immunogens. Outside the lab, he enjoys working out and spending time with his wife, Melody, and their dog, Sully.